Microfluidic Modeling of Cell−Cell Interactions in Malaria Pathogenesis

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Microfluidic Modeling of Cell−Cell Interactions in Malaria Pathogenesis

The clinical outcomes of human infections by Plasmodium falciparum remain highly unpredictable. A complete understanding of the complex interactions between host cells and the parasite will require in vitro experimental models that simultaneously capture diverse host-parasite interactions relevant to pathogenesis. Here we show that advanced microfluidic devices concurrently model (a) adhesion o...

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ژورنال

عنوان ژورنال: PLoS Pathogens

سال: 2007

ISSN: 1553-7374

DOI: 10.1371/journal.ppat.0030099